TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO

The TOR kinase, which is present in the functionally distinct complexes TORC1 and TORC2, is essential for growth but associated with disease and aging. Elucidation of how TOR modulates lifespan will identify mechanisms of fundamental importance in aging, and TOR functions. Here we show that when TOR...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Robida-Stubbs, Stacey, Glover-Cutter, Kira, Lamming, Dudley W., Mizunuma, Masaki, Narasimhan, Sri Devi, Neumann-Haefelin, Elke, Sabatini, David M., Blackwell, T. Keith
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3348514/
https://ncbi.nlm.nih.gov/pubmed/22560223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.04.007
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker