DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO

Insulin/IGF-1 signaling controls metabolism, stress resistance and aging in Caenorhabditis elegans by regulating the activity of the DAF-16/FoxO transcription factor (TF). However, the function of DAF-16 and the topology of the transcriptional network that it crowns remain unclear. Using chromatin p...

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Autori principali: Schuster, Eugene, McElwee, Joshua J, Tullet, Jennifer M A, Doonan, Ryan, Matthijssens, Filip, Reece-Hoyes, John S, Hope, Ian A, Vanfleteren, Jacques R, Thornton, Janet M, Gems, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950082/
https://ncbi.nlm.nih.gov/pubmed/20706209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.54
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