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DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
Insulin/IGF-1 signaling controls metabolism, stress resistance and aging in Caenorhabditis elegans by regulating the activity of the DAF-16/FoxO transcription factor (TF). However, the function of DAF-16 and the topology of the transcriptional network that it crowns remain unclear. Using chromatin p...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Nature Publishing Group
2010
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950082/ https://ncbi.nlm.nih.gov/pubmed/20706209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.54 |
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