Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence

In Caenorhabditis elegans, ablation of germline stem cells (GSCs) extends lifespan, but also increases fat accumulation and alters lipid metabolism, raising the intriguing question of how these effects might be related. Here, we show that a lack of GSCs results in a broad transcriptional reprogrammi...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:eLife
Main Authors: Steinbaugh, Michael J, Narasimhan, Sri Devi, Robida-Stubbs, Stacey, Moronetti Mazzeo, Lorenza E, Dreyfuss, Jonathan M, Hourihan, John M, Raghavan, Prashant, Operaña, Theresa N, Esmaillie, Reza, Blackwell, T Keith
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541496/
https://ncbi.nlm.nih.gov/pubmed/26196144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07836
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares