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Cysteine sulfenylation directs IRE-1 to activate the SKN-1/Nrf2 antioxidant response
Emerging evidence suggests that many proteins may be regulated through cysteine modification, but the extent and functions of this signaling remain largely unclear. The endoplasmic reticulum (ER) transmembrane protein IRE-1 maintains ER homeostasis by initiating the unfolded protein response (UPR(ER...
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Publicado no: | Mol Cell |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996358/ https://ncbi.nlm.nih.gov/pubmed/27540856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.019 |
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