Cysteine sulfenylation directs IRE-1 to activate the SKN-1/Nrf2 antioxidant response

Emerging evidence suggests that many proteins may be regulated through cysteine modification, but the extent and functions of this signaling remain largely unclear. The endoplasmic reticulum (ER) transmembrane protein IRE-1 maintains ER homeostasis by initiating the unfolded protein response (UPR(ER...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Hourihan, John M., Moronetti Mazzeo, Lorenza E., Fernández-Cárdenas, L. Paulette, Blackwell, T. Keith
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996358/
https://ncbi.nlm.nih.gov/pubmed/27540856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.07.019
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