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Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK
We previously reported that gliotoxin (GT), the major virulence factor of the mold Aspergillus fumigatus causing invasive aspergillosis (IA) in immunocompromised patients, induces apoptosis in a Bak-dependent manner. The signaling pathway leading to Bak activation and subsequent mitochondrial outer...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770331/ https://ncbi.nlm.nih.gov/pubmed/23832115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.78 |
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