Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK

We previously reported that gliotoxin (GT), the major virulence factor of the mold Aspergillus fumigatus causing invasive aspergillosis (IA) in immunocompromised patients, induces apoptosis in a Bak-dependent manner. The signaling pathway leading to Bak activation and subsequent mitochondrial outer...

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Bibliografske podrobnosti
Main Authors: Geissler, A, Haun, F, Frank, D O, Wieland, K, Simon, M M, Idzko, M, Davis, R J, Maurer, U, Borner, C
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770331/
https://ncbi.nlm.nih.gov/pubmed/23832115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.78
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