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JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

Yes-associated protein (YAP) regulates DNA damage and chemosensitivity, as well as functioning as a pro-growth, cell size regulator. For both of its roles, regulation by phosphorylation is crucial. We undertook an in vitro screen to identify novel YAP kinases to discover new signaling pathways to be...

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Библиографические подробности
Главные авторы: Tomlinson, V, Gudmundsdottir, K, Luong, P, Leung, K-Y, Knebel, A, Basu, S
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032333/
https://ncbi.nlm.nih.gov/pubmed/21364637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.7
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