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JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

Yes-associated protein (YAP) regulates DNA damage and chemosensitivity, as well as functioning as a pro-growth, cell size regulator. For both of its roles, regulation by phosphorylation is crucial. We undertook an in vitro screen to identify novel YAP kinases to discover new signaling pathways to be...

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Detalhes bibliográficos
Main Authors: Tomlinson, V, Gudmundsdottir, K, Luong, P, Leung, K-Y, Knebel, A, Basu, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032333/
https://ncbi.nlm.nih.gov/pubmed/21364637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.7
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