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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
The c-Jun NH(2)-terminal kinase (JNK) is activated when cells are exposed to environmental stress, including UV radiation. Gene disruption studies demonstrate that JNK is essential for UV-stimulated apoptosis mediated by the mitochondrial pathway by a Bax/Bak-dependent mechanism. Here, we demonstrat...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The National Academy of Sciences
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151358/ https://ncbi.nlm.nih.gov/pubmed/12591950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0438011100 |
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