JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
The c-Jun NH(2)-terminal kinase (JNK) is activated when cells are exposed to environmental stress, including UV radiation. Gene disruption studies demonstrate that JNK is essential for UV-stimulated apoptosis mediated by the mitochondrial pathway by a Bax/Bak-dependent mechanism. Here, we demonstrat...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12591950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0438011100 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|