Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK

We previously reported that gliotoxin (GT), the major virulence factor of the mold Aspergillus fumigatus causing invasive aspergillosis (IA) in immunocompromised patients, induces apoptosis in a Bak-dependent manner. The signaling pathway leading to Bak activation and subsequent mitochondrial outer...

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Bibliografiske detaljer
Main Authors: Geissler, A, Haun, F, Frank, D O, Wieland, K, Simon, M M, Idzko, M, Davis, R J, Maurer, U, Borner, C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770331/
https://ncbi.nlm.nih.gov/pubmed/23832115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.78
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