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Apoptosis induced by the fungal pathogen gliotoxin requires a triple phosphorylation of Bim by JNK
We previously reported that gliotoxin (GT), the major virulence factor of the mold Aspergillus fumigatus causing invasive aspergillosis (IA) in immunocompromised patients, induces apoptosis in a Bak-dependent manner. The signaling pathway leading to Bak activation and subsequent mitochondrial outer...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770331/ https://ncbi.nlm.nih.gov/pubmed/23832115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.78 |
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