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HLA-C–Dependent Prevention of Leukemia Relapse by Donor Activating KIR2DS1
BACKGROUND: Of the cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT), acute myeloid leukemia (AML) is most sensitive to natural killer (NK)–cell reactivity. The activating killer-cell immunoglobulin-like receptor (KIR) 2DS1 has ligand specificity for HLA-C2 antigens and...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767478/ https://ncbi.nlm.nih.gov/pubmed/22931314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1200503 |
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