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Donor activating KIR3DS1 is associated with decreased acute GVHD in unrelated allogeneic hematopoietic stem cell transplantation

The natural killer cell receptor KIR3DS1 is associated with improved outcome in malignancies, infections, and autoimmune diseases, but data for the impact of KIR3DS1 in HSCT are inconsistent. Using genomic DNA from the National Marrow Donor Program, we performed donor KIR genotyping for 1087 patient...

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Detalhes bibliográficos
Main Authors: Venstrom, Jeffrey M., Gooley, Ted A., Spellman, Stephen, Pring, James, Malkki, Mari, Dupont, Bo, Petersdorf, Effie, Hsu, Katharine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858471/
https://ncbi.nlm.nih.gov/pubmed/20124216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-236943
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