Natural Killer Cells: Tolerance to Self and Innate Immunity to Viral Infection and Malignancy

Por Yokoyama, Wayne M., Altfeld, Marcus, Hsu, Katharine C.
Publicado em 2009

Development of a Novel Multiplex PCR Assay to Detect Functional Subtypes of KIR3DL1 Alleles

Por Boudreau, Jeanette E., Le Luduec, Jean-Benoît, Hsu, Katharine C.
Publicado em 2014

Phenotypic and Functional Activation of Hyporesponsive KIR(neg)NKG2A(neg) Human NK-Cell Precursors Requires IL-12p70 Provided by Poly(I:C)-Matured Monocyte-Derived Dendritic Cells

Por Curran, Shane A., Romano, Emanuela, Kennedy, Michael G., Hsu, Katharine C., Young, James W.
Publicado em 2014

KIR3DS1 specific D0 domain polymorphisms disrupt KIR3DL1 surface expression and HLA binding()

Por Mulrooney, Tiernan J., Zhang, Aaron C., Goldgur, Yehuda, Boudreau, Jeanette E., Hsu, Katharine C.
Publicado no J Immunol (2015)

KIR3DL1 and HLA-B density and binding calibrate NK education and response to HIV

Por Boudreau, Jeanette E., Mulrooney, Tiernan J., Le Luduec, Jean-Benoît, Barker, Edward, Hsu, Katharine C.
Publicado no J Immunol (2016)

Breaking tolerance to self, circulating natural killer cells expressing inhibitory KIR for non-self HLA exhibit effector function after T cell–depleted allogeneic hematopoietic cel...

Por Yu, Junli, Venstrom, Jeffrey M., Liu, Xiao-Rong, Pring, James, Hasan, Reenat S., O'Reilly, Richard J., Hsu, Katharine C.
Publicado em 2009

Donor activating KIR3DS1 is associated with decreased acute GVHD in unrelated allogeneic hematopoietic stem cell transplantation

Por Venstrom, Jeffrey M., Gooley, Ted A., Spellman, Stephen, Pring, James, Malkki, Mari, Dupont, Bo, Petersdorf, Effie, Hsu, Katharine C.
Publicado em 2010

KIR and HLA genotypes have no identifiable role in single unit dominance following double unit umbilical cord blood transplantation

Por Tarek, Nidale, Gallagher, Meighan M., Chou, Joanne F., Lubin, Marissa N., Heller, Glenn, Barker, Juliet N., Hsu, Katharine C.
Publicado no Bone Marrow Transplant (2014)

Phase II Study of Haploidentical Natural Killer Cell Infusion for Treatment of Relapsed or Persistent Myeloid Malignancies Following Allogeneic Hematopoietic Cell Transplantation

Por Shaffer, Brian C., Le Ludec, Jean-Benoit, Forlenza, Christopher, Jakubowski, Ann A., Perales, Miguel-Angel, Young, James W., Hsu, Katharine C.
Publicado no Biol Blood Marrow Transplant (2016)

Cell-extrinsic MHC class I molecule engagement augments human NK cell education programmed by cell-intrinsic MHC class I

Por Boudreau, Jeanette E., Liu, Xiao-Rong, Zhao, Zeguo, Zhang, Aaron, Shultz, Leonard D., Greiner, Dale L., Dupont, Bo, Hsu, Katharine C.
Publicado no Immunity (2016)

NK cell tolerance of self-specific activating receptor KIR2DS1 in individuals with cognate HLA-C2 ligand

Por Pittari, Gianfranco, Liu, Xiao-Rong, Selvakumar, Annamalai, Zhao, Zeguo, Merino-Plaza, Ernesto, Huse, Morgan, Chewning, Joseph H., Hsu, Katharine C., Dupont, Bo
Publicado em 2013

KIR3DL1 Allelic Polymorphism and HLA-B Epitopes Modulate Response to Anti-GD2 Monoclonal Antibody in Patients With Neuroblastoma

Por Forlenza, Christopher J., Boudreau, Jeanette E., Zheng, Junting, Le Luduec, Jean-Benoît, Chamberlain, Elizabeth, Heller, Glenn, Cheung, Nai-Kong V., Hsu, Katharine C.
Publicado no J Clin Oncol (2016)

Improved outcome in HLA-identical sibling hematopoietic stem-cell transplantation for acute myelogenous leukemia predicted by KIR and HLA genotypes

Por Hsu, Katharine C., Keever-Taylor, Carolyn A., Wilton, Andrew, Pinto, Clara, Heller, Glenn, Arkun, Knarik, O'Reilly, Richard J., Horowitz, Mary M., Dupont, Bo
Publicado em 2005

HLA-C–Dependent Prevention of Leukemia Relapse by Donor Activating KIR2DS1

Por Venstrom, Jeffrey M., Pittari, Gianfranco, Gooley, Ted A., Chewning, Joseph H., Spellman, Stephen, Haagenson, Michael, Gallagher, Meighan M., Malkki, Mari, Petersdorf, Effie, Dupont, Bo, Hsu, Katharine C.
Publicado em 2012

Human Dendritic Cells Mitigate NK-Cell Dysfunction Mediated by Nonselective JAK1/2 Blockade

Por Curran, Shane A., Shyer, Justin A., St. Angelo, Erin T., Talbot, Lillian R., Sharma, Sneh, Chung, David J., Heller, Glenn, Hsu, Katharine C., Betts, Brian C., Young, James W.
Publicado no Cancer Immunol Res (2016)

KIR and HLA Genotypes are Associated with Disease Progression and Survival following Autologous Hematopoietic Stem Cell Transplantation for High-Risk Neuroblastoma

Por Venstrom, Jeffrey M., Zheng, Junting, Noor, Nabila, Danis, Karen E., Yeh, Alice W., Cheung, Irene Y., Dupont, Bo, O’Reilly, Richard J., Cheung, Nai-Kong V., Hsu, Katharine C.
Publicado em 2009

Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment

Por Tarek, Nidale, Le Luduec, Jean-Benoit, Gallagher, Meighan M., Zheng, Junting, Venstrom, Jeffrey M., Chamberlain, Elizabeth, Modak, Shakeel, Heller, Glenn, Dupont, Bo, Cheung, Nai-Kong V., Hsu, Katharine C.
Publicado em 2012

HLA alleles determine differences in human natural killer cell responsiveness and potency

Por Kim, Sungjin, Sunwoo, John B., Yang, Liping, Choi, Taewoong, Song, Yun-Jeong, French, Anthony R., Vlahiotis, Anna, Piccirillo, Jay F., Cella, Marina, Colonna, Marco, Mohanakumar, Thalachallour, Hsu, Katharine C., Dupont, Bo, Yokoyama, Wayne M.
Publicado em 2008

Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation

Por Shi, Jumei, Tricot, Guido, Szmania, Susann, Rosen, Nancy, Garg, Tarun K., Malaviarachchi, Priyangi A., Moreno, Amberly, DuPont, Bo, Hsu, Katharine C., Baxter-Lowe, Lee Ann, Cottler-Fox, Michele, Shaughnessy, John D., Barlogie, Bart, van Rhee, Frits
Publicado em 2008

T-CELL DEPLETED UNRELATED DONOR STEM CELL TRANSPLANTATION PROVIDES FAVORABLE DISEASE-FREE SURVIVAL FOR ADULTS WITH HEMATOLOGIC MALIGNANCIES

Por Jakubowski, Ann A., Small, Trudy N., Kernan, Nancy A., Castro-Malaspina, Hugo, Collins, Nancy, Koehne, Guenther, Hsu, Katharine C., Perales, Miguel A., Papanicolaou, Genovefa, van den Brink, Marcel R.M., O’Reilly, Richard J., Young, James W., Papadopoulos, Esperanza B.
Publicado em 2011