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Phenotypic and Functional Activation of Hyporesponsive KIR(neg)NKG2A(neg) Human NK-Cell Precursors Requires IL-12p70 Provided by Poly(I:C)-Matured Monocyte-Derived Dendritic Cells
A functionally responsive natural killer (NK)-cell repertoire requires the acquisition of inhibitory NKG2A and killer immunoglobulin-like receptors (KIR) through pathways that remain undefined. Functional donor NK cells expressing KIRs for non-self class I MHC ligands contribute to a positive outcom...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185245/ https://ncbi.nlm.nih.gov/pubmed/25023628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0054-T |
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