NK Cell Terminal Differentiation: Correlated Stepwise Decrease of NKG2A and Acquisition of KIRs

BACKGROUND: Terminal differentiation of NK cells is crucial in maintaining broad responsiveness to pathogens and discriminating normal cells from cells in distress. Although it is well established that KIRs, in conjunction with NKG2A, play a major role in the NK cell education that determines whethe...

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Hauptverfasser: Béziat, Vivien, Descours, Benjamin, Parizot, Christophe, Debré, Patrice, Vieillard, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917352/
https://ncbi.nlm.nih.gov/pubmed/20700504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011966
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