HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2(+) NK cells in Lassa virus infection

BACKGROUND: Lassa virus (LASV) is the etiologic agent of an acute hemorrhagic fever endemic in West Africa. Natural killer (NK) cells control viral infections in part through the interaction between killer cell immunoglobulin-like receptors (KIRs) and their ligands. LASV infection is associated with...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wauquier, Nadia, Petitdemange, Caroline, Tarantino, Nadine, Maucourant, Christopher, Coomber, Moinya, Lungay, Victor, Bangura, James, Debré, Patrice, Vieillard, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413685/
https://ncbi.nlm.nih.gov/pubmed/30711514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.048
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