HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2(+) NK cells in Lassa virus infection

BACKGROUND: Lassa virus (LASV) is the etiologic agent of an acute hemorrhagic fever endemic in West Africa. Natural killer (NK) cells control viral infections in part through the interaction between killer cell immunoglobulin-like receptors (KIRs) and their ligands. LASV infection is associated with...

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Udgivet i:EBioMedicine
Main Authors: Wauquier, Nadia, Petitdemange, Caroline, Tarantino, Nadine, Maucourant, Christopher, Coomber, Moinya, Lungay, Victor, Bangura, James, Debré, Patrice, Vieillard, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
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Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413685/
https://ncbi.nlm.nih.gov/pubmed/30711514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.048
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