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Intrahepatic IL-10 Maintains NKG2A(+)Ly49(−) Liver NK Cells in a Functionally Hyporesponsive State

The tolerogenic nature of the liver allows daily exposure to gut-derived foreign Ags without causing inflammation, but it may facilitate persistent infection in the liver. NK cells play a central role in innate immunity, as well as in shaping the adaptive immune response. We hypothesized that the na...

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Autori principali: Lassen, Matthew G., Lukens, John R., Dolina, Joseph S., Brown, Michael G., Hahn, Young S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885840/
https://ncbi.nlm.nih.gov/pubmed/20124099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901362
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