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NKG2D receptor–mediated NK cell function is regulated by inhibitory Ly49 receptors

Interaction of the activating ligand H60 with NKG2D receptor constitutes a major stimulatory pathway for natural killer (NK) cells. The influence of inhibitory Ly49 receptors on NKG2D-mediated activation is not clearly understood. Here we show that the magnitude of NKG2D-mediated cytotoxicity is dir...

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Detalhes bibliográficos
Main Authors: Regunathan, Jeyarani, Chen, Yuhong, Wang, Demin, Malarkannan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889208/
https://ncbi.nlm.nih.gov/pubmed/15328154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-03-1075
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