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The balancing act: Inhibitory Ly49 regulate NKG2D-mediated NK cell functions
NK cells use NKG2D receptor to recognize ‘induced-self’. In apparent violation of the ‘missing-self’ hypothesis, NK cells stimulated through NKG2D can lyse target cells despite normal expression levels of MHC class I molecules. Although, ‘overriding’ of the inhibitory by the activating signals had b...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752866/ https://ncbi.nlm.nih.gov/pubmed/16737823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2006.04.002 |
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