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KIR3DS1 specific D0 domain polymorphisms disrupt KIR3DL1 surface expression and HLA binding()
KIR3DL1 is a polymorphic inhibitory receptor that modulates natural killer cell activity through interacting with HLA-A and HLA-B alleles that carry the Bw4 epitope. Amino acid polymorphisms throughout KIR3DL1 impact receptor surface expression and affinity for HLA. KIR3DL1/S1 encodes inhibitory and...
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| Опубликовано в: : | J Immunol |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506867/ https://ncbi.nlm.nih.gov/pubmed/26109640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500243 |
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