HLA-C–Dependent Prevention of Leukemia Relapse by Donor Activating KIR2DS1

BACKGROUND: Of the cancers treated with allogeneic hematopoietic stem-cell transplantation (HSCT), acute myeloid leukemia (AML) is most sensitive to natural killer (NK)–cell reactivity. The activating killer-cell immunoglobulin-like receptor (KIR) 2DS1 has ligand specificity for HLA-C2 antigens and...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Venstrom, Jeffrey M., Pittari, Gianfranco, Gooley, Ted A., Chewning, Joseph H., Spellman, Stephen, Haagenson, Michael, Gallagher, Meighan M., Malkki, Mari, Petersdorf, Effie, Dupont, Bo, Hsu, Katharine C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767478/
https://ncbi.nlm.nih.gov/pubmed/22931314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1200503
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi