High HLA-DP Expression and Graft-versus-Host Disease

BACKGROUND: Transplantation of hematopoietic cells from unrelated donors can cure blood disorders but carries a significant risk of acute graft-versus-host disease (GVHD). The risk is higher when the recipient and donor are HLA-DPB1–mismatched, but the mechanisms leading to GVHD are unknown. The HLA...

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Détails bibliographiques
Publié dans:N Engl J Med
Auteurs principaux: Petersdorf, Effie W., Malkki, Mari, O’hUigin, Colm, Carrington, Mary, Gooley, Ted, Haagenson, Michael D., Horowitz, Mary M., Spellman, Stephen R., Wang, Tao, Stevenson, Philip
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560117/
https://ncbi.nlm.nih.gov/pubmed/26267621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1500140
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