TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia

Frontotemporal lobar degeneration (FTLD) is the second leading cause of dementia in individuals under age 65. In many patients, the predominant pathology includes neuronal cytoplasmic or intranuclear inclusions of ubiquitinated TAR DNA binding protein 43 (FTLDTDP). Recently, a genome-wide associatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Nicholson, Alexandra M., Finch, NiCole A., Wojtas, Aleksandra, Baker, Matt C., Perkerson, Ralph B., Castanedes-Casey, Monica, Rousseau, Linda, Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Hsiung, Ging-Yuek R., Mackenzie, Ian R., Finger, Elizabeth, Boeve, Bradley F., Ertekin-Taner, Nilüfer, Graff-Radford, Neill R., Dickson, Dennis W., Rademakers, Rosa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766501/
https://ncbi.nlm.nih.gov/pubmed/23742080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12329
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