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TMEM106B haplotypes have distinct gene expression patterns in aged brain

BACKGROUND: Single nucleotide polymorphisms (SNPs) inherited as one of two common haplotypes at the transmembrane protein 106B (TMEM106B) locus are associated with the risk of multiple neurodegenerative diseases, including frontotemporal lobar degeneration with pathological inclusions of TDP-43. Amo...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Ren, Yingxue, van Blitterswijk, Marka, Allen, Mariet, Carrasquillo, Minerva M., Reddy, Joseph S., Wang, Xue, Beach, Thomas G., Dickson, Dennis W., Ertekin-Taner, Nilüfer, Asmann, Yan W., Rademakers, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029036/
https://ncbi.nlm.nih.gov/pubmed/29970152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0268-2
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