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In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protein kinase-dependent pathway

BACKGROUND: Tuberculosis (TB) of the central nervous system (CNS) is characterized by extensive tissue inflammation, driven by molecules that cleave extracellular matrix such as matrix metalloproteinase (MMP)-1 and MMP-3. However, relatively little is known about the regulation of these MMPs in the...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Green, Justin A, Rand, Lucinda, Moores, Rachel, Dholakia, Shruti, Pezas, Theodore, Elkington, Paul T, Friedland, Jon S
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765428/
https://ncbi.nlm.nih.gov/pubmed/23978194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-107
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