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Crosslinking the ligand-binding domain dimer interface locks kainate receptors out of the main open state
Kainate-selective ionotropic glutamate receptors (iGluRs) fulfil key roles in the CNS, making them the subject of detailed structural and functional analyses. Although they are known to gate a channel pore with high and low ion-permeation rates, it is still not clear how switches between these gatin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3764634/ https://ncbi.nlm.nih.gov/pubmed/23713029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.253666 |
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