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Stability of ligand-binding domain dimer assembly controls kainate receptor desensitization
AMPA and kainate receptors mediate fast synaptic transmission. AMPA receptor ligand-binding domains form dimers, which are key functional units controlling ion-channel activation and desensitization. Dimer stability is inversely related to the rate and extent of desensitization. Kainate and AMPA rec...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2688536/ https://ncbi.nlm.nih.gov/pubmed/19339989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.86 |
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