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Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions

The activity of many ligand-gated ion channels and cell surface receptors is modulated by small molecules and ions, but an understanding of the underlying molecular mechanisms is scarce. For kainate, but not AMPA subtype glutamate receptors, the binding of Na(+) and Cl(−) ions to discrete, electrost...

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Detalhes bibliográficos
Main Authors: Chaudhry, Charu, Plested, Andrew J. R., Schuck, Peter, Mayer, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718364/
https://ncbi.nlm.nih.gov/pubmed/19617541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904175106
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