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Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions
The activity of many ligand-gated ion channels and cell surface receptors is modulated by small molecules and ions, but an understanding of the underlying molecular mechanisms is scarce. For kainate, but not AMPA subtype glutamate receptors, the binding of Na(+) and Cl(−) ions to discrete, electrost...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718364/ https://ncbi.nlm.nih.gov/pubmed/19617541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904175106 |
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