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High-resolution crystal structure reveals molecular details of target recognition by bacitracin
Bacitracin is a metalloantibiotic agent that is widely used as a medicine and feed additive. It interferes with bacterial cell-wall biosynthesis by binding undecaprenyl-pyrophosphate, a lipid carrier that serves as a critical intermediate in cell wall production. Despite bacitracin’s broad use, the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3761639/ https://ncbi.nlm.nih.gov/pubmed/23940351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308268110 |
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