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High-resolution crystal structure reveals molecular details of target recognition by bacitracin

Bacitracin is a metalloantibiotic agent that is widely used as a medicine and feed additive. It interferes with bacterial cell-wall biosynthesis by binding undecaprenyl-pyrophosphate, a lipid carrier that serves as a critical intermediate in cell wall production. Despite bacitracin’s broad use, the...

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Detalhes bibliográficos
Main Authors: Economou, Nicoleta J., Cocklin, Simon, Loll, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761639/
https://ncbi.nlm.nih.gov/pubmed/23940351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308268110
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