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The high resolution structure of tyrocidine A reveals an amphipathic dimer
Tyrocidine A, one of the first antibiotics ever to be discovered, is a cyclic decapeptide that binds to membranes of target bacteria, disrupting their integrity. It is active against a broad spectrum of Gram-positive organisms, and has recently engendered interest as a potential scaffold for develop...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980540/ https://ncbi.nlm.nih.gov/pubmed/24530898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2014.01.033 |
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