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Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

The site-specific incorporation of bioorthogonal groups via genetic code expansion provides a powerful general strategy for site-specifically labelling proteins with any probe. However, the slow reactivity of the bioorthogonal functional groups that can be encoded genetically limits the utility of t...

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Detaylı Bibliyografya
Asıl Yazarlar: Lang, Kathrin, Davis, Lloyd, Torres-Kolbus, Jessica, Chou, Chungjung, Deiters, Alexander, Chin, Jason W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758886/
https://ncbi.nlm.nih.gov/pubmed/22437715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1250
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