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Synthesis of Non-linear Protein Dimers through a Genetically Encoded Thiol-ene Reaction

Site-specific incorporation of bioorthogonal unnatural amino acids into proteins provides a useful tool for the installation of specific functionalities that will allow for the labeling of proteins with virtually any probe. We demonstrate the genetic encoding of a set of alkene lysines using the ort...

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Autors principals: Torres-Kolbus, Jessica, Chou, Chungjung, Liu, Jihe, Deiters, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152134/
https://ncbi.nlm.nih.gov/pubmed/25181502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105467
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