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Genetically Encoded Light-Activated Transcription for Spatio-Temporal Control of Gene Expression and Gene Silencing in Mammalian Cells

Photocaging provides a method to spatially and temporally control biological function and gene expression with high resolution. Proteins can be photochemically controlled through the site-specific installation of caging groups on amino acid side chains that are essential for protein function. The ph...

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Main Authors: Hemphill, James, Chou, Chungjung, Chin, Jason W., Deiters, Alexander
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188981/
https://ncbi.nlm.nih.gov/pubmed/23931657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4051026
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