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Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction
The site-specific incorporation of bioorthogonal groups via genetic code expansion provides a powerful general strategy for site-specifically labelling proteins with any probe. However, the slow reactivity of the bioorthogonal functional groups that can be encoded genetically limits the utility of t...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758886/ https://ncbi.nlm.nih.gov/pubmed/22437715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1250 |
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