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Genetically Encoded Unstrained Olefins for Live Cell Labeling with Tetrazine Dyes
A number of non-canonical amino acids (NCAAs) with unstrained olefins are genetically encoded using mutant pyrrolysyl-tRNA synthetase- [Formula: see text] pairs. These NCAAs readily undergo inverse electron-demand Diels-Alder cycloadditions with tetrazine dyes, leading to selective labeling of prote...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4184966/ https://ncbi.nlm.nih.gov/pubmed/25224663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc06435f |
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