Disruption of Myc-Max Heterodimerization with Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5

The c-Myc (Myc) oncoprotein is a high-value therapeutic target given that it is deregulated in multiple types of cancer. However, potent small molecule inhibitors of Myc have been difficult to identify, particularly those whose mechanism relies on blocking the association between Myc and its obligat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wang, Huabo, Chauhan, Jay, Hu, Angela, Pendleton, Kelsey, Yap, Jeremy L., Sabato, Philip E., Jones, Jace W., Perri, Mariarita, Yu, Jianshi, Cione, Erika, Kane, Maureen A., Fletcher, Steven, Prochownik, Edward V.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2013
विषय:
Research Papers
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757250/
https://ncbi.nlm.nih.gov/pubmed/23801058
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