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BCL-x(L)/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells
The acute promyelocytic leukemia (APL) subtype of acute myeloid leukemia (AML) is characterized by chromosomal translocations that result in fusion proteins, including the promyelocytic leukemia-retinoic acid receptor, alpha fusion protein (PML-RARα). All-trans retinoic acid (atRA) treatment is the...
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| Publicado no: | Exp Cell Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727751/ https://ncbi.nlm.nih.gov/pubmed/25088254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.07.024 |
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