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NLS-RARα Promotes Proliferation and Inhibits Differentiation in HL-60 Cells
A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein between the retinoic acid receptor α (RARα) and a myeloid gene product called PML. Studies have reported that neutrophil elastase (NE) cleaves bcr-1-derived PML-RARα in early...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Ivyspring International Publisher
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917113/ https://ncbi.nlm.nih.gov/pubmed/24516348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.6518 |
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