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PML(NLS(-)) Inhibits Cell Apoptosis and Promotes Proliferation in HL-60 Cells

Promyelocytic leukemia (PML) is a cell-growth suppressor, and PML-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Studies have reported that neutrophil elastase(NE) cleaved bcr-1-derived PML-RARα in early myeloid cells leading to the removal of nu...

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Detalhes bibliográficos
Main Authors: Gao, Yuan-Mei, Zhong, Liang, Zhang, Xi, Hu, Xiu-Xiu, Liu, Bei-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3607234/
https://ncbi.nlm.nih.gov/pubmed/23532460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.5560
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