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PML(NLS(-)) Inhibits Cell Apoptosis and Promotes Proliferation in HL-60 Cells
Promyelocytic leukemia (PML) is a cell-growth suppressor, and PML-retinoic acid receptor α (PML-RARα) is known as a fusion gene of acute promyelocytic leukemia (APL). Studies have reported that neutrophil elastase(NE) cleaved bcr-1-derived PML-RARα in early myeloid cells leading to the removal of nu...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Ivyspring International Publisher
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3607234/ https://ncbi.nlm.nih.gov/pubmed/23532460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.5560 |
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