Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma

Human cancer genomes are highly complex, making it challenging to identify specific drivers of cancer growth, progression, and tumor maintenance. To bypass this obstacle, we have applied array comparative genomic hybridization (array CGH) to zebrafish embryonal rhabdomyosaroma (ERMS) and utilized cr...

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Main Authors: Chen, Eleanor Y., Dobrinski, Kimberly P., Brown, Kim H., Clagg, Ryan, Edelman, Elena, Ignatius, Myron S., Chen, Jin Yun Helen, Brockmann, Jillian, Nielsen, G. Petur, Ramaswamy, Sridhar, Keller, Charles, Lee, Charles, Langenau, David M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757044/
https://ncbi.nlm.nih.gov/pubmed/24009521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003727
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