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Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis
Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRAS(G12D) expression at different stages during muscle development. Several zebrafish promoter...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699286/ https://ncbi.nlm.nih.gov/pubmed/23821038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087858 |
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