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Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis

Rhabdomyosarcoma is a pediatric malignancy thought to arise from the uncontrolled proliferation of myogenic cells. Here, we have generated models of rhabdomyosarcoma in the zebrafish by inducing oncogenic KRAS(G12D) expression at different stages during muscle development. Several zebrafish promoter...

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Bibliografiset tiedot
Päätekijät: Storer, Narie Y., White, Richard M., Uong, Audrey, Price, Emily, Nielsen, G. Petur, Langenau, David M., Zon, Leonard I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699286/
https://ncbi.nlm.nih.gov/pubmed/23821038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087858
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