Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma

Human cancer genomes are highly complex, making it challenging to identify specific drivers of cancer growth, progression, and tumor maintenance. To bypass this obstacle, we have applied array comparative genomic hybridization (array CGH) to zebrafish embryonal rhabdomyosaroma (ERMS) and utilized cr...

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Hauptverfasser: Chen, Eleanor Y., Dobrinski, Kimberly P., Brown, Kim H., Clagg, Ryan, Edelman, Elena, Ignatius, Myron S., Chen, Jin Yun Helen, Brockmann, Jillian, Nielsen, G. Petur, Ramaswamy, Sridhar, Keller, Charles, Lee, Charles, Langenau, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757044/
https://ncbi.nlm.nih.gov/pubmed/24009521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003727
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