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Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma

Human cancer genomes are highly complex, making it challenging to identify specific drivers of cancer growth, progression, and tumor maintenance. To bypass this obstacle, we have applied array comparative genomic hybridization (array CGH) to zebrafish embryonal rhabdomyosaroma (ERMS) and utilized cr...

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Autors principals: Chen, Eleanor Y., Dobrinski, Kimberly P., Brown, Kim H., Clagg, Ryan, Edelman, Elena, Ignatius, Myron S., Chen, Jin Yun Helen, Brockmann, Jillian, Nielsen, G. Petur, Ramaswamy, Sridhar, Keller, Charles, Lee, Charles, Langenau, David M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757044/
https://ncbi.nlm.nih.gov/pubmed/24009521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003727
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