The CRTC1-NEDD9 Signaling Axis Mediates Lung Cancer Progression Caused by LKB1 Loss

Somatic mutation of the tumor suppressor gene LKB1 occurs frequently in lung cancer where it causes tumor progression and metastasis, but the underlying mechanisms remain mainly unknown. Here, we show that the oncogene NEDD9 is an important downstream mediator of lung cancer progression evoked by LK...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Feng, Yan, Wang, Ye, Wang, Zuoyun, Fang, Zhaoyuan, Li, Fei, Gao, Yijun, Liu, Hongyan, Xiao, Tian, Li, Fuming, Zhou, Yang, Zhai, Qiwei, Liu, Xiaolong, Sun, Yihua, Bardeesy, Nabeel, Wong, Kwok-kin, Chen, Haiquan, Xiong, Zhi-qi, Ji, Hongbin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755891/
https://ncbi.nlm.nih.gov/pubmed/23074285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-1909
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky