Modification of Triclosan Scaffold in Search of Improved Inhibitors for Enoyl-Acyl Carrier Protein (ACP) Reductase in Toxoplasma gondii

Through our focused effort to discover new and effective agents against toxoplasmosis, a structure-based drug design approach was utilized to develop a series of potent inhibitors of the enoyl-acyl carrier protein (ACP) reductase (ENR) enzyme in Toxoplasma gondii (TgENR). Modifications to positions...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Stec, Jozef, Fomovska, Alina, Afanador, Gustavo A., Muench, Stephen P., Zhou, Ying, Lai, Bo-Shiun, Bissati, Kamal El, Hickman, Mark R., Lee, Patty J., Leed, Susan E., Auschwitz, Jennifer M., Sommervile, Caroline, Woods, Stuart, Roberts, Craig W., Rice, David, Prigge, Sean T., McLeod, Rima, Kozikowski, Alan P.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3755765/
https://ncbi.nlm.nih.gov/pubmed/23776166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201300050
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker