Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD(+)

The binding of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum (PfENR) with its substrates and inhibitors has been analysed by SPR (surface plasmon resonance). The binding of the substrate analogue crotonoyl-CoA and coenzyme NADH to PfENR was monitored in real time by observing...

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Detalhes bibliográficos
Main Authors: Kapoor, Mili, Mukhi, P. L. Swarna, Surolia, Namita, Suguna, K., Surolia, Avadhesha
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133882/
https://ncbi.nlm.nih.gov/pubmed/15125687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040228
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