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Kinetic and structural analysis of the increased affinity of enoyl-ACP (acyl-carrier protein) reductase for triclosan in the presence of NAD(+)
The binding of enoyl-ACP (acyl-carrier protein) reductase from Plasmodium falciparum (PfENR) with its substrates and inhibitors has been analysed by SPR (surface plasmon resonance). The binding of the substrate analogue crotonoyl-CoA and coenzyme NADH to PfENR was monitored in real time by observing...
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Main Authors: | , , , , |
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格式: | Artigo |
語言: | Inglês |
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Portland Press Ltd.
2004
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133882/ https://ncbi.nlm.nih.gov/pubmed/15125687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040228 |
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